The UC Davis Nuclear Magnetic Resonance (NMR) Facility is equipped with state-of-the-art magnetic resonance equipment suitable for liquids, solids and imaging experiments. Below is a short summary of our available instrumentation. You can see more information about each spectrometer by clicking on the tabs to the left.
MedSci-1D
The MedSci-1D Facility houses 6 NMR Spectrometers. The 600 and 800 MHz Bruker Avance III spectrometers are usually equipped with cryoprobes for increased sensitivity over conventional NMR probes. These cryoprobes are ideally suited for NMR structure determination of proteins, nucleic acids and other biomolecules.
There are two 500 MHz (11.75 T) Spectrometers. The Bruker Avance DRX spectrometer is usually equipped with a 5 mm 1H/BB probe with an X-channel tunable from 15N to 31P. This spectrometer is also capable of both low-temperature and high-temperature experiments. It is generally used for high resolution liquids samples. The 500 MHz BRUKER AVANCE I NMR spectrometer is equipped with an 11.74T wide bore Bruker magnet specifically designated for solid-state-NMR experiments. Depending on the features of the researchers’ projects, various probes are available with difference sample sizes ad spinning speeds. The 2.5, and 7 mm probes are H/BB CPMAS probes with the broadband tunes to 15N-31P. A 4mm triple-resonance (H/BB/BB) CPMAS probe is cable of running X-Y correlation MAS NMR experiments, for example, H/N/C, H/C/P, H/Si/Al. The 4 mm and 7 mm low-gamma CPMAS probes cover the frequency range of 12-50MHz (41K – 51N). The wideline probe is capable of running static NMR experiment at VT range of -150C to 400C, and covers the frequency range from 109Ag to 31P.
The other 2 spectrometers are capable of in vivo spectroscopy and imaging (MRI). The 400 MHz Bruker DRX spectrometer is a vertical-bore instrument with both spectroscopy and microimaging capabilities, and has both Topspin and Paravision 4 software for spectrometer control. The 7T (300 MHz) MRI instrument is a horizontal-bore spectrometer ideal for small-animal imaging.
Chemistry
Chemistry room 93 houses a Varian 600 MHz NMR spectrometer using VnmrJ software and a Bruker 400 MHz NMR spectrometer with Topspin 3.2 running ICONNMR. The instrument of choice for most organic/inorganic chemists interested in routine 1D and 2D NMR experiments is the 400 MHz Bruker spectrometer in room 93. This spectrometer is equipped with a 5 mm 1H/X broadband probe with autotuning/automatching capabilities.
Chemistry Annex room 3470 is home to a single Mercury Plus (Varian) 300 MHz NMR spectrometer primarily used for teaching purposes.
Scheduling
Trained users can reserve NMR experiment time by visiting our Online Scheduler
