500 MHz Bruker Avance DRX NMR

Our 500 MHz Bruker Avance DRX Spectrometer is our most popular instrument for X-nuclei experiments or for high- and low-temperature experiments.  It is typically equipped with a 5 mm Bruker 1H / X Broadband observe probe with the X channel tunable from 15N - 31P. Other probes are also available for specialized use.

Spectrometer Information

  • Bruker Avance DRX 500 MHz NMR
  • Capable of low and high temperature experiments
  • BCU-05 or LN2 for low temperature
  • Topspin 1.3 on Linux CentOS 5 Workstation

Probes

  • 5mm Bruker PABBO BB/19F - 1H/D   Z-Grad
    • BB / 1H / 2H Channels
    • Low and high temperature
    • X-nuclei direct detection
  • 10 mm Bruker BBO
  • 5 mm Bruker TXI 1H - 13C/15N - D   Z-Grad
  • 5 mm Bruker TXI 1H - 13C/15N - D   XYZ-Grad

Examples of Spectrometer Use

  • 31P NMR used to investigate dynamics of uranyl peroxide nanoclusters at various temperatures and pressures. http://onlinelibrary.wiley.com/doi/10.1002/anie.201301973/abstract
  • 19F NMR used to monitor dissociation of drug-delivering nanoparticles in vitro.
  • 31P NMR used to monitor ATP and ADP concentrations in ischemic and drug-treated rabbit hearts.